《生命科学》 2023, 35(4): 509-518
光照调控红曲霉生长发育及聚酮类代谢产物合成的研究进展
摘 要:
光在自然界普遍存在并多层次全方位影响着生物的生长和代谢。红曲霉作为最早被人类驯化的微生物之一,被广泛应用于食品及医药领域。红曲霉通过蓝色、红色和绿色光感受器感知不同波长的光,而这些光通过复杂的信号通路影响菌体的生长和代谢。该文分别介绍蓝光、红光、绿光等对红曲霉生长发育以及红曲色素、桔霉素等聚酮类代谢产物合成的影响及相应光感受器的研究进展,提出了进一步探讨光调控红曲霉生长发育及聚酮类代谢产物合成的研究思路,为揭示光调控红曲霉生长发育及聚酮类代谢产物合成的机制提供参考。
通讯作者:高梦祥 , Email:mgao@yangtzeu.edu.cn
Abstract:
Light is ubiquitous in nature and affects the growth and metabolism of organisms at multiple levels and in all directions. Monascus, as one of the earliest microorganisms domesticated by humans, is widely used in the fields of food and medicine. Monascus perceives different wavelengths of light through blue, red, and green photoreceptors, and the light influences the growth and metabolism of Monascus through complex pathways. This paper reviews the research status of blue, red, and green light affecting the growth, development and the synthesis of polyketide metabolites (Monascus pigment and citrinin) of Monascus and the corresponding photoreceptors. The further research ideas are proposed that light regulates the growth, development and the synthesis of polyketone metabolites of Monascus, so as to provide a reference for revealing the mechanism of light regulating growth and development and the synthesis of polyketone metabolites of Monascus.
Communication Author:GAO Meng-Xiang , Email:mgao@yangtzeu.edu.cn