《生命科学》 2022, 34(9): 1101-1107
通讯作者：李培山 , Email:firstname.lastname@example.org
Neutrophils, as important effector cells in the innate immune system, play a key role in the coordination of immune and inflammatory responses. As the first line of defense against bacterial and fungal infections, neutrophils have the ability to kill invading pathogens. In the pathological state of malignant tumors, neutrophils have dual functions of promoting or inhibiting tumor development, according to changing phenotypes. How to inhibit the tumor-promoting activity and enhance the tumor-suppressive activity of neutrophils is an important scientific issue in tumor therapy. The tumor-promoting effect of neutrophils has already been introduced, while the tumor-suppressive effect of neutrophils is less involved in current reviews. This article focuses on the biological characteristics of neutrophils and their tumor-inhibiting mechanisms, aming to provide references for targeting neutrophils to treat tumors.
Communication Author：LI Pei-Shan , Email:email@example.com