《生命科学》 2021, 33(3): 355-362
通讯作者：王金娥 , Email:email@example.com
At present, with the continuous improvement of people's living standards, the incidence of obesity and related diseases is getting higher and higher. Although physical exercise can increase energy consumption to some extent, it is not enough to cause negative energy balance and weight loss. Activation of brown and beige adipocytes can lead to increased energy consumption, weight loss and increased insulin sensitivity. Therefore, more and more studies have focused on the molecular mechanism of these two thermogenic adipose tissues to increase energy consumption, so as to find targets for the treatment of obesity and related diseases. This paper systematically
reviews the similarities and differences of the classification, developmental pedigree, thermogenic characteristics and thermogenic mechanism of the two kinds of thermogenic adipose tissue, and puts forward the shortcomings and development direction at the present stage, in order to provide new ideas for the treatment of obesity and related diseases.
Communication Author：WANG Jin-E , Email:firstname.lastname@example.org