倪佳俐1 , 侯亚义2 , 窦 环2,*
1南京大学生命科学学院,南京 210023 2南京大学医学院,南京 210023

摘 要:


通讯作者:窦 环 , Email:douhuan@nju.edu.cn

Research progress on the B lymphoid tyrosine kinase
NI Jia-Li1 , HOU Ya-Yi2 , DOU Huan2,*
1School of Life Sciences, Nanjing University, Nanjing 210023, China 2Medical School of Nanjing University, Nanjing 210023, China


B lymphoid tyrosine kinase (BLK) is one of the SRC kinase family members, which exhibits tyrosine protein kinase activity. As an “intermediate molecule”, BLK is involved in signaling transduction of physiological processes such as cell development, cell migration and proliferation. BLK generally manifests as decreased expression or diminished activity in the course of disease progression. Research on BLK has significant implications for the study of molecular mechanisms of disease and clinical treatment. Our review highlighted the molecular characteristics, functions and its roles in diseases.

Communication Author:DOU Huan , Email:douhuan@nju.edu.cn

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