《生命科学》 2021, 33(2): 139-147
通讯作者：沈万华 , Email:email@example.com
Flotillin-1 and flotillin-2 are involved in many cellular physiological processes, including regulation of cell adhesion, cargo endocytosis, protein sorting and recycling, and cell migration. Flotillins are also closely related to the occurrence and development of some degenerative diseases and tumors. In this review, we first introduced the structure and distribution of flotillins. Then, we summarized the recent progress of flotillins since its discovery, including the impact on morphogenesis, neural growth and function, as well as the regulation of multiple signal transduction pathways. Finally, the role of flotillins in the research of disease mechanism and clinical diagnosis and treatment was prospected.
Communication Author：SHEN Wan-Hua , Email:firstname.lastname@example.org