中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2009, 21(5): 715-719
肿瘤干细胞研究进展
潘秋辉1,宋尔卫2*
(1中山大学附属第二医院医学研究中心,广州510120;2中山大学附属第二医院乳腺外科,广州510120)
摘 要:在过去的十年中,肿瘤干细胞(cancer stem cell/tumor-initiating cell, CSC/TIC)虽然受到广泛重视,但也是争论的焦点。如何正确认识CSCs假说,以及CSCs的生物学特点和CSCs的治疗应用这些问题都存在巨大的争议。该文对CSCs的起源、分离鉴定的方法,以及信号通路、微环境等对CSCs的调控关系,肿瘤的最佳治疗途径等问题进行综述。

    
关键词:干细胞;肿瘤干细胞;肿瘤治疗;分选鉴定

    
中图分类号:R730.231  文献标识码:A  

    
 

    
 

    
 
 
Research progress of cancer stem cells
PAN Qiu-hui1, SONG Er-wei2*
(1 Medical Research Center, second Affiliated Hospital, Sun Yat-sen University, Guangzhou 510120, China2 Department of Breast Surgery, Second Affiliated Hospital, Sun Yat-sen University, Guangzhou 510120, China);
 

    
Abstract: The investigation and study of cancer stem cells (CSCs) have received enormous attention over the past decade but remain topics of considerable controversy. Opinions about the validity of the CSC hypothesis, the biological properties of CSCs, and the relevance of CSCs to cancer therapy differ widely. In the following text, we discuss the origin, the identification, regulatory pathway, microenviroment and the new potential therapeutic targets elucidated by considering cancer as a problem in stem cell biology.

    
Key words: stem cell; cancer stem cell; cancer therapy; identification of sorfing
 
首页 | 刊物简介 | 编委会 | 投稿须知 | 广告业务 | 过刊浏览 | 联系我们
中国科学院上海生命科学信息中心《生命科学》编辑部
Copyright © 2012-2015 《生命科学》编辑部 All Rights Reserved.
沪ICP备05033115号-30
您是第2954929 位访问者,欢迎!