中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2009, 21(3): 408-411
基于受体的药物高通量筛选研究进展
冯璐璐,赵霞霞,李发荣*
(陕西师范大学生命科学学院,西安710062)
摘 要:受体是药物筛选的重要靶标,基于受体的药物高通量筛选是药物筛选的主要类型之一。本文根据受体作用原理,按照检测对象的不同,从直接与间接检测的角度,将基于受体的药物高通量筛选进行了分类,总结了基于受体的几种不同的药物筛选模型,并简要介绍了高通量筛选技术在中药研究中的应用,对药物筛选的发展进行了展望。
关键词:受体模型;高通量筛选;中药研究
 
Progress of high-throughput drug screening based on the receptor model
FENG Lu-lu, ZHAO Xia-xia, LI Fa-rong*
(College of Life Sciences, Shaanxi Normal University, Xi{$39}an 710062, China)
Abstract: The receptor is attractive as an important target for drug screening. Receptor-based high-throughput screening is one of the main techniques in modern drug discovery. According to the mechanism of drug-receptor interaction and different object of detection, this paper reviews the classification of the high-throughput screening models based on the receptor, simply introduces the application of high-throughput screening technique in traditional Chinese medicine research, and discusses its future development.
Key words: receptor model; high-throughput screening; Chinese medicine research
 
首页 | 刊物简介 | 编委会 | 投稿须知 | 广告业务 | 过刊浏览 | 联系我们
中国科学院上海生命科学信息中心《生命科学》编辑部
Copyright © 2012-2015 《生命科学》编辑部 All Rights Reserved.
沪ICP备05033115号-30
您是第2954184 位访问者,欢迎!