中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2008, 20(3): 454-
RNA 编辑功能的研究进展
郑玉姝,赵 朴*,刘兴友
(河南科技学院动物科学学院,新乡 453003)
摘 要:RNA编辑产生RNA和蛋白质多样性。最近研究表明,RNA编辑在抗体多样性、病毒应答、剪接调节和miRNA调节方面发挥重要作用,并且越来越多的证据表明,RNA编辑与脑发育和神经性疾病的发生有关。因此,深入理解RNA编辑的功能有望促进我们理解这一与疾病诊断和治疗有关的有趣机制。
关键词:RNA编辑;抗体多样性;病毒应答;剪接调节;miRNA调节
中图分类号:Q71;Q522 文献标识码:A
 
Progress in the functions of RNA editing
ZHENG Yu-shu, ZHAO Pu* , LIU Xing-you
(Department of Animal Science and Technology, Henan Institute of Science and Technology, Xinxiang 453003, China)
Abstract: RNA editing generates RNA and protein diversity. Recent research highlights that RNA editing plays important roles in antibody diversification,viral response, splicing regulation and miRNA regulation. And increasing evidence suggests that RNA editing is involved in the development of the brain and the pathogenesis of neurological diseases. Therefore, better understanding the functions of RNA editing is expected to increase our understanding of this intriguing mechanism which is endowed with diagnostic and therapeutic implications.
Key words: RNA editing; antibody diversification; viral response; splicing regulation; miRNA regulation
 
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