中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2008, 20(1): 14-
分子生物光子学的进展
王桂英*,付 国, 徐至展
(中国科学院上海光学精密机械研究所 强场激光物理国家重点实验室,上海201800)

摘 要:随着分子生物学和标记技术的进步,光学成像和分析有了很快的发展,无论是从理论上还是应用上都有所突破,展现了良好的前景。本文综述了近年来在分子生物探测中光子学的情况,简介了几种突破光学衍射极限的探测方法,着重阐明了与生化技术密切相关的荧光共振能量转移和荧光相关光谱显微术及其在分子生物学中的应用。
关键词:光学成像和分析;生物光子学;单分子探测
中图分类号:Q63;Q7  文献标识码:A

 
An advance in molecular biophotonics
WANG Gui-ying*, FU Guo, XU Zhi-zhan
(State Key Laboratory of High Field Laser Physics, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China)

Abstract: Whether on theory or in applications, optical imaging and analysis have gained great progresses with the developments of biological studies and labeling techniques and which exhibits a good prospect. Recently, the biophotonics advances and several new ways of breaking diffraction limit on the optical imaging are described in this paper. In particular, the progresses on the fluorescence resonance energy transfer microscopy and fluorescence correlation spectroscopy, as well as their applications for resolving molecular biologic problem are discussed in detail.
Key words: optical imaging and analysis; biophotonics; single molecule detection  

 
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