中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2006, 18(1): 75-
干细胞向胰岛样细胞诱导分化的研究进展
陆 琰,张 洹*
暨南大学医学院血液病研究所, 广州510632
摘 要:目前,糖尿病患病率呈现上升趋势,它已成为严重危害人类健康的疾病之一。胰岛细胞移植可以用来治疗1型和部分2型糖尿病,但由于供体细胞来源匮乏,寻找新的细胞来源成了当务之急。近年来,随着细胞移植和组织工程的日益发展,干细胞研究为新型胰岛的来源开辟了新的途径。本文综述了近年来干细胞分化为胰岛样细胞的研究进展、存在问题和可能的解决途径。
关键词:干细胞;糖尿病;细胞治疗
 
Research progress of differentiation of stem cells into islet-like cells
LU Yan, ZHANG Yuan*
Insititute of Hematology, Jinan University, Guangzhou 510632, China
Abstract: The morbidity rate of diabetes mellitus is increasing at present, which is a serious disease damaging human being抯 health. The transplantation of pancreatic islet cells has been used to treat the diabetes type 1 and 2. However, it is necessary to search new sources of insulin-secreting cells for cell therapy of diabetes mellitus due to lacking of sufficient donor cells. With the development of cell therapy and tissue engineering in recent years, the new way of new islet cells from stem cells has be found, which can provide new islets for curing of diabetes. The progress of differentiation from stem cells into islet-like cells, problems and prospect will be discussed in the review.
Key words: stem cell; diabetes mellitus; cell therapy
 
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