中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2006, 18(5): 477-
单核细胞趋化蛋白受体的研究进展
鲍荣辉*,刘先哲
三峡大学医学院,宜昌443002
摘 要:单核细胞趋化蛋白及其受体在机体免疫应答中(免疫调节、器官形成、调节造血和神经元通讯)发挥了重要作用,同时也广泛参与某些疾病的发病机制(动脉粥样硬化、感染炎症性疾病及肿瘤等)。因此,有关趋化性细胞因子的新理论和技术可为临床治疗某些疾病提供了新思路。本文简要地综述单核细胞趋化蛋白受体的生物学特性、生物学作用及对心血管疾病的影响作用。
关键词:单核细胞趋化蛋白;受体;疾病
 
Research progress of monocyte chemoattractant protein receptor
BAO Rong-Hui*, LIU Xian-Zhe
Medical College of China Three Gorges University, Yichang 443002, China
Abstract: Monocyte chemoattractant protein and their receptors in immunity reply (immunoloregulation, organogenesis, hematopoiesis and neuronal communication) have played important roles, and also widely participate in the pathogenesy of diseases (atherosclerosis, inflammatory, tumor, etc). Therefore, the new theory and the technology about chemokines may provide some new ways for clinical treatment of certain diseases. This review focuses on the biological charactoristics and functions of cc chemokine receptor (CCR), and its effects on the cardiovascular diseases.
Key words: monocyte chemoattractant protein; receptor; disease
 
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