中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2013, 25(9): 915-921
丝状真菌小RNA研究进展
弭宝彬1,2,李娟娟1,2,陈国华3,茆振川3*
(1 湖南省蔬菜研究所,长沙 410125;2 中南大学研究生院隆平分院,长沙 410125;3 中国农业科学院蔬菜花卉研究所,北京 100081)
摘 要:粗糙脉孢菌是研究真菌小RNA 的模式生物。在物种进化过程中,小RNA 调节机制发生了相应的变化。综述了真菌小RNA 调控机制的最新研究进展及相关组件,对了解物种进化机制有着重要的意义。随着小分子RNA 调控机制研究的不断深入,更多新型的小分子RNA 已被发现,这将为RNA 干扰研究开拓新的研究领域和发展方向。
    关键词:丝状真菌;小RNA ;disiRNA ;qiRNA ;MSUD
 
Research progress of filamentous fungi small RNAs
    
MI Bao-Bin1, LI Juan-Juan1, CHEN Guo-Hua3, MAO Zhen-Chuan3*
    
(1 Vegetable Research Institute, Hunan Academy of Agricultural Sciences, Changsha 410125, China; 2 Longping Branch of Graduate School, Central South University, Changsha 410125, China; 3 Institute of Vegetable and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China)
    
Abstract: Neurospora crassa is the model organism for research on small RNA in fungi. The regulatory mechanisms on small RNAs vary accordingly with evolution of species. The latest progresses of the regulatory mechanisms on fungi small RNA and their core components are summarized, which will achieve a further comprehension of the evolution of species. Recently, more and more new small RNAs have been discovered as a result of the development of regulation mechanisms of small RNAs, which can exploit a new research field and orientation for the study of RNA interference.
    Key words: filamentous fungi; small RNA; disiRNA; qiRNA; MSUD
 
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