中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2013, 25(5): 532-538
植物miR164家族研究进展
牟桂萍,纪春艳,许东林,周国辉*
(华南农业大学资源环境学院,广州 510642)
摘 要: miRNA是真核细胞中一类长约22 nt的非编码小分子RNA,它们可通过碱基序列互补配对与靶mRNA分子结合并将后者降解,从而对靶基因实施转录后水平负调控,在生物发育调节及抗逆反应中发挥重要作用。miR164家族是植物特有的一类miRNA,其主要的靶基因是植物NAC家族转录因子。从miR164的特点、对NAC家族的调控、表达时序及组织分布特征和对环境及生物胁迫的响应,以及miR164及其靶基因的验证方法等方面,作一简要综述。
关键词:microRNA;miR164;基因调控;靶基因
 
Advances in plant miR164 family
MOU Gui-Ping, JI Chun-Yan, XU Dong-Lin, ZHOU Guo-Hui*
(College of Natural Resources and Environment, South China Agricultural University, Guangzhou 510642, China)
Abstract: MicroRNAs (miRNAs) are a class of non-coding small RNA molecules of ~22 nt in eukaryotic cells. They can complementarily combine with the mRNAs of target genes and cause their degradation, conducting post- transcriptionally negative regulation and thus playing important roles in a variety of biological growth/development processes and stress-resistance responses. The miR164 family is a group of plant-specific miRNAs, whose target genes mainly are the NAC transcriptional factor family. This paper presents a brief summary on the characteristics of the miR164 family, their regulation of NAC genes, their spatial-temporal expression and distribution and their responses to environmental or biological stress, as well as the methods of validation of miR164s and their target genes.
Key words: microRNA; miR164; gene regulation; target genes
 
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