中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2011, 23(5): 477-481
成骨细胞中经典Wnt/β-catenin通路研究进展
许 兵1,刘 慧1,许应星1,吴 岩1,肖鲁伟1,童培建2*
(1 浙江中医药大学第一临床医学院,杭州 310053;2 浙江省中医院骨伤科,杭州 310012)
摘 要:Wnt/β-catenin经典通路在成骨细胞的分化增殖中起着重要作用。目前研究表明,调节任何一个经典Wnt/β-catenin信号转导通路中的因子都能影响成骨细胞的分化增殖。总结经典Wnt/β-catenin通路中各个因子与成骨细胞分化增殖的关系,以便进一步具体深入研究经典Wnt/β-catenin通路对成骨细胞的影响。
关键词:成骨细胞;Wnt/β-catenin;因子  
 
Development of the classic Wnt/β-catenin pathway in osteoblasts
XU Bing1, LIU Hui1, XU Ying-Xing1, WU Yan1, XIAO Lu-Wei1, TONG Pei-Jian2*
(1The First College of Clinic Medicine, Zhejiang Traditional Chinese Medical University, Hangzhou 310053, China; 2 Orthopedics, Chinese Medicine Hospital of Zhejiang Province, Hangzhou 310012, China)
Abstract: The classical Wnt/β-catenin pathway plays an important role in the differentiation and proliferation of osteoblasts. Now the researches show that the regulation of any factors in classical Wnt/β-catenin signal transduction pathway can influence the differentiation and proliferation of osteoblasts. This paper summarizes the relationship between the respective factors in the classic Wnt/β-catenin pathway and the differentiation and proliferation of osteoblasts in order to further study the classical Wnt/β-catenin pathway of osteoblasts.
Key words: osteoblast; Wnt/β-catenin; factor
 
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