中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2010, 22(5): 416-420
冬凌草甲素抗肿瘤作用的研究进展
张文静1, 黄启来1*, 华子春1,2*
1澳门科技大学中医药学院和澳门药物与健康应用研究所,澳门; 2南京大学医药与生物技术国家重点实验室,南京210093
摘 要:冬凌草甲素是从唇形科香茶菜属植物中分离出的对映贝壳杉烯二萜类有机化合物,具有广泛的抗肿瘤活性。该文将就冬凌草甲素抗肿瘤活性的化学构效关系及其抗肿瘤机制做一综述。
关键词:冬凌草甲素(oridonin,Ori);化学结构;抗肿瘤
 
Research progress in oridonin for antitumor activity
ZHANG Wen-jing1, HUANG Qi-lai1*, HUA Zi-chun1,2*
1 Faculty of Traditional Chinese Medicine and Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau, China; 2 State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, China)
Abstract: Oridonin, a diterpenoid isolated from Rabdosia rubescens(Hemsl.)Hara, has been proved to possess remarkable anticancer potential. The current review focuses on relationship between the chemical structure, modification and antitumor activity of oridonin, and discusses the molecular mechanisms underlying its antitumor activity.
Key words: oridonin; chemical structure; antitumor
 
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