中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2016, 28(7): 777-780
肝再生磷酸酶-2的最新研究进展
殷岑楠,吴琛耘,王兆军*
(上海交通大学医学院免疫学与微生物学系,感染免疫实验室,上海 200025)
摘 要:肝再生磷酸酶-2 (phosphatase of regenerating liver-2, PRL-2) 是蛋白酪氨酸磷酸酶家族的成员。作为一种蛋白磷酸酶,PRL 家族因其成员PRL-3 在肿瘤组织中的特异性高表达而备受人们关注。在近几年的研究中,人们逐渐把目光转向了在正常人体各个组织中均高表达的PRL-2 分子,现综述了PRL-2 的生物学功能及其在肿瘤相关研究中的最新进展。
 
The latest research progress in PRL-2
YIN Cen-Nan, WU Chen-Yun, WANG Zhao-Jun*
(Laboratory of Infection and Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China)
Abstract: Phosphatase of regenerating liver-2 (PRL-2) is a member of protein tyrosine phosphatases family. As a protein phosphatase, PRL-3, the third member of PRL family, has attracted much interest due to its specific high expression in tumor tissues. However, as PRL-2 is widely expressed in normal adult tissues, researchers have become more and more interested in PRL-2. Here, we provide an overview of the physcial function of PRL-2 and its role in cancer.
 
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