中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2014, 26(8): 874-881
昆虫成虫蜕皮激素研究进展
杨栋梁,郝 婧,王彦男,奚耕思*
(陕西师范大学生命科学学院动物生殖与发育实验室,西安 710062)
摘 要:绝大多数成体昆虫羽化后,幼虫期间负责蜕皮激素合成的前胸腺即发生退化,但在一些内部生理及外部环境因子的调控下,某些成体组织( 如生殖腺) 可扮演类似前胸腺的角色合成与分泌蜕皮激素。蜕皮激素的功能发挥是经受体介导的,包括核受体( 如EcR/USP) 和膜受体( 如DopEcR),它们广泛表达于成体许多组织,参与成虫行为、生殖、寿命、滞育及免疫应答等众多方面的调节,对维持基本的生理功能具有重要作用。就成虫蜕皮激素的产生组织及影响其滴度的因素、成虫蜕皮激素受体概述与组织分布、成虫蜕皮激素信号通路的功能发挥等研究进展方面加以综述。
 
Research progress of ecdysone in adult insects
YANG Dong-Liang, HAO Jing, WANG Yan-Nan, XI Geng-Si*
(Laboratory of Animal Reproduction and Development, College of Life Science, Shaanxi Normal University, Xi'an 710062, China)
Abstract: For most of insects, prothoracic glands, which undertake the synthesis and secretion of ecdysone during metamorphosis, degenerate after emergence, but some adult tissues parallel to larval prothoracic glands, such as gonads, can product ecdysone under the control of both inner physiological and external environmental factors. Ecdysone exerts functions through receptors comprising both nuclear receptor (such as EcR/USP) and membrane receptors (such as DopEcR), which are widely expressed in many adult tissues, participating in the regulation of vital biological events including adult behaviors, reproduction, lifespan, diapause and innate immunity, and play an important role in maintenance of essential physiological function. In this paper, we mainly review and discuss the ecdysteroidogenic tissue and affecting factors of ecdysone, ecdysone receptors and their tissue distribution, as well as roles and research progress of ecdysone signaling in adult insects.
 
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