中国科技核心期刊
CN:31-1600/Q
ISSN:1004-0374
“健康与疾病的免疫”国际学术研讨会通知      关于有网站冒充本刊网站的声明
《生命科学》 2014, 26(8): 799-803
线粒体与肿瘤发生发展
冯 浩,张 箴,沙保勇,高兴春*
(西安医学院基础医学研究所,西安 710021)
摘 要:肿瘤的发生发展是一个十分复杂的生物学过程。随着研究的深入,人们逐渐认识到线粒体不仅是重要的细胞器,而且在肿瘤的发生发展中也起着重要的作用,与肿瘤的能量代谢异常、活性氧自由基升高、组织浸润和转移能力、细胞死亡抵抗等密切相关。就近年来线粒体与肿瘤发生发展的关系研究做一综述。
 
Mitochondria and tumor development
FENG Hao, ZHANG Zhen, SHA Bao-Yong, GAO Xing-Chun*
(Institute of Basic Medical Science, Xi’an Medical University, Xi’an 710021, China)
Abstract: Tumor development is an extremely complicated biological process. With further research, it is gradually recognized that mitochondria play an essential role in tumor development not just important organelles. Mitochondria are highly dynamic organelles, which are related to the following characteristics such as abnormal energy metabolism of tumor, increasing of reactive oxygen species, ability of tissue invasion and metastasis and resistance to cell death. This paper reviews the relationship between mitochondria and tumor development.
 
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